Many other spammers use ``hit and run'' spamming in which they get a trial dial-up account at an Internet provider for a few days, send tens of thousands of messages, then abandon the account (unless the provider notices what they're doing and cancels it first), leaving the unsuspecting provider to clean up the mess. Many spammers have done this tens or dozens of times, forcing the providers to waste staff time both on the cleanup and on monitoring their trial accounts for abuse.
Spammers know that people don't want to hear from them, and generally put fake return addresses on their messages so that they don't have to bear the cost of receiving responses from people to whom they've send messages. Whenever possible, they use the "disposable" trial ISP accounts mentioned above so the ISP bears the cost of cleaning up after them. I could go on, but you get the idea. It's hard to think of another line of business where the general ethical level is so low.
Some people have taken to forging their own From: and Reply-to: lines in their posts. They might add an easily-recognized 'spam-block' to their address, or they might use those header lines to tell folks where to look for their real address (usually in the sig). Some attempt to boast of their elitist-Unix-nerd-programmer capabilities by burying their email address in a maze of code. Such measures, while effective, are frowned upon by some as 'giving in' to the bulk emailers.
If you do a lot of web browsing, be careful about filling out forms; some outfits take such action as carte blanche to stuff your mailbox. There are also those who sell addresses collected in this manner. Don't assume that because you are visiting the site of a 'reputable company' that this will not happen to you.
If you are using Netscape Navigator 2.0, it is possible for your email address to be collected without your knowledge when you visit a web site. This bug was quickly corrected, and versions 2.01 and above do not have this problem. (See: http://ng.netgate.net/~barry/badJavaSc.html )